Ĭlinical signs of OA are lameness, stiffness, loss of joint function, and mobility. The OA should be considered a final common pathway of joint damage secondary to a multitude of inciting events, many of which may also be unrecognized. Īging alone is an unlikely cause of OA: in veterinary literature, it has been suggested that 20% of dogs above one year old are affected by the progressive changes of OA. Osteoarthritis (OA) is a slowly progressive disease characterized by articular cartilage degradation, subchondral bone sclerosis, periarticular proliferation of new bone, and chronic inflammation of synovial membrane. This does not alter our adherence to PLOS ONE policies on sharing data and materials. There are no additional products in development or marketed products to declare. curcuVet is contained in a dietetic complementary feed produced by Aurora Biofarma, so-called Lecurpet. curcuVet is a registered march (Indena s.p.a., Milan, Italy).
No patented products in development are present in this study. The funders had no additional role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Ĭompeting interests: AN is a scientific consultant of Aurora Biofarma and receives funding in the form of salary. The specific roles of this author are articulated in the ‘author contributions’ section. Aurora Biofarma provided support in the form of nutraceutical preparation and in the form of salary to AN. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.ĭata Availability: All relevant data are within the manuscript.įunding: AN is a scientific consultant of Aurora Biofarma. Received: MaAccepted: Published: May 28, 2021Ĭopyright: © 2021 Caterino et al. PLoS ONE 16(5):Įditor: Ewa Tomaszewska, University of Life Sciences in Lublin, POLAND
(2021) Clinical efficacy of Curcuvet and Boswellic acid combined with conventional nutraceutical product: An aid to canine osteoarthritis. Citation: Caterino C, Aragosa F, Della Valle G, Costanza D, Lamagna F, Piscitelli A, et al.
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